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Treatment Cancer

cali48
15.06.2018

Content:

  • Treatment Cancer
  • Treatment types
  • Featured articles
  • There are many types of cancer treatment. The types of treatment that you receive will depend on the type of cancer you have and how. Information on cancer treatment methods, specific anticancer drugs, and drug development and approval. Research updates, cancer treatment. Your treatment depends on where your cancer is, how big it is, whether it has spread, and your general health. There are different types of treatment you might .

    Treatment Cancer

    Sipuleucel-T is a vaccine-like strategy in late clinical trials for prostate cancer in which dendritic cells from the patient are loaded with prostatic acid phosphatase peptides to induce a specific immune response against prostate-derived cells. Allogeneic hematopoietic stem cell transplantation "bone marrow transplantation" from a genetically non-identical donor can be considered a form of immunotherapy, since the donor's immune cells will often attack the tumor in a phenomenon known as graft-versus-tumor effect.

    For this reason, allogeneic HSCT leads to a higher cure rate than autologous transplantation for several cancer types, although the side effects are also more severe. NK cells and CTLs primarily kill the cancer cells when they are developed. Under normal conditions, the immune system utilizes checkpoint proteins as negative feedback mechanisms to return to homeostasis once pathogens have been cleared from the body. In tumor microenvironment, cancer cells can commandeer this physiological regulatory system to "put a brake" on the anti-cancer immune response and evade immune surveillance.

    The growth of some cancers can be inhibited by providing or blocking certain hormones. Common examples of hormone-sensitive tumors include certain types of breast and prostate cancers.

    Blocking estrogen or testosterone is often an important additional treatment. In certain cancers, administration of hormone agonists, such as progestogens may be therapeutically beneficial. Angiogenesis inhibitors prevent the extensive growth of blood vessels angiogenesis that tumors require to survive. Some, such as bevacizumab , have been approved and are in clinical use. One of the main problems with anti-angiogenesis drugs is that many factors stimulate blood vessel growth in cells normal or cancerous.

    Anti-angiogenesis drugs only target one factor, so the other factors continue to stimulate blood vessel growth. Other problems include route of administration , maintenance of stability and activity and targeting at the tumor vasculature. Synthetic lethality arises when a combination of deficiencies in the expression of two or more genes leads to cell death, whereas a deficiency in only one of these genes does not. The deficiencies can arise through mutations, epigenetic alterations or inhibitors of one or both of the genes.

    Cancer cells are frequently deficient in a DNA repair gene. This DNA repair defect either may be due to mutation or, often, epigenetic silencing see epigenetic silencing of DNA repair. Non-tumorous cells, with the initial pathway intact, can survive.

    There are five different stages of colon cancer, and these five stages all have treatment. Stage 0, is where the patient is required to undergo surgery to remove the polyp American Cancer Society [29]. Stage 1, depending on the location of the cancer in the colon and lymph nodes, the patient undergoes surgery just like Stage 0. Stage 2 patients undergoes removing nearby lymph nodes, but depending on what the doctor says, the patent might have to undergo chemotherapy after surgery if the cancer is at higher risk of coming back.

    Stage 3, is where the cancer has spread all throughout the lymph nodes but not yet to other organs or body parts. The last a patient can get is Stage 4. Stage 4 patients only undergo surgery if it is for the prevention of the cancer, along with pain relief. If the pain continues with these two options, the doctor might recommended radiation therapy.

    The main treatment strategy is Chemotherapy due to how aggressive the cancer becomes in this stage not only to the colon but to the lymph nodes. Although the control of the symptoms of cancer is not typically thought of as a treatment directed at the cancer, it is an important determinant of the quality of life of cancer patients, and plays an important role in the decision whether the patient is able to undergo other treatments.

    Although doctors generally have the therapeutic skills to reduce pain, Chemotherapy-induced nausea and vomiting , diarrhea, hemorrhage and other common problems in cancer patients, the multidisciplinary specialty of palliative care has arisen specifically in response to the symptom control needs of this group of patients.

    Pain medication , such as morphine and oxycodone , and antiemetics , drugs to suppress nausea and vomiting, are very commonly used in patients with cancer-related symptoms. Improved antiemetics such as ondansetron and analogues, as well as aprepitant have made aggressive treatments much more feasible in cancer patients. Cancer pain can be associated with continuing tissue damage due to the disease process or the treatment i.

    Although there is always a role for environmental factors and affective disturbances in the genesis of pain behaviors, these are not usually the predominant etiologic factors in patients with cancer pain. Some patients with severe pain associated with cancer are nearing the end of their lives, but in all cases palliative therapies should be used to control the pain. Issues such as social stigma of using opioids , work and functional status, and health care consumption can be concerns and may need to be addressed in order for the person to feel comfortable taking the medications required to control his or her symptoms.

    The typical strategy for cancer pain management is to get the patient as comfortable as possible using the least amount of medications possible but opioids, surgery, and physical measures are often required. Historically, doctors were reluctant to prescribe narcotics to terminal cancer patients due to addiction and respiratory function suppression.

    The palliative care movement, a more recent offshoot of the hospice movement, has engendered more widespread support for preemptive pain treatment for cancer patients. The World Health Organization also noted uncontrolled cancer pain as a worldwide problem and established a "ladder" as a guideline for how practitioners should treat pain in patients who have cancer [30].

    Cancer-related fatigue is a very common problem for cancer patients, and has only recently become important enough for oncologists to suggest treatment, even though it plays a significant role in many patients' quality of life. Hospice is a group that provides care at the home of a person that has an advanced illness with a likely prognosis of less than 6 months. As most treatments for cancer involve significant unpleasant side effects, a patient with little realistic hope of a cure or prolonged life may choose to seek comfort care only, forgoing more radical therapies in exchange for a prolonged period of normal living.

    This is an especially important aspect of care for those patients whose disease is not a good candidate for other forms of treatment. In these patients, the risks related to the chemotherapy may actually be higher than the chance of responding to the treatment, making further attempts to cure the disease impossible. Of note, patients on hospice can sometimes still get treatments such as radiation therapy if it is being used to treat symptoms, not as an attempt to cure the cancer.

    Clinical trials , also called research studies, test new treatments in people with cancer. The goal of this research is to find better ways to treat cancer and help cancer patients. Clinical trials test many types of treatment such as new drugs, new approaches to surgery or radiation therapy, new combinations of treatments, or new methods such as gene therapy. A clinical trial is one of the final stages of a long and careful cancer research process.

    The search for new treatments begins in the laboratory, where scientists first develop and test new ideas. If an approach seems promising, the next step may be testing a treatment in animals to see how it affects cancer in a living being and whether it has harmful effects.

    Of course, treatments that work well in the lab or in animals do not always work well in people. Studies are done with cancer patients to find out whether promising treatments are safe and effective. Patients who take part may be helped personally by the treatment they receive.

    They get up-to-date care from cancer experts, and they receive either a new treatment being tested or the best available standard treatment for their cancer. At the same time, new treatments also may have unknown risks, but if a new treatment proves effective or more effective than standard treatment, study patients who receive it may be among the first to benefit.

    There is no guarantee that a new treatment being tested or a standard treatment will produce good results. In children with cancer, a survey of trials found that those enrolled in trials were on average not more likely to do better or worse than those on standard treatment; this confirms that success or failure of an experimental treatment cannot be predicted. Exosomes are lipid-covered microvesicles shed by solid tumors into bodily fluids, such as blood and urine. Current research is being done attempting to use exosomes as a detection and monitoring method for a variety of cancers.

    The same process can also be used to more accurately monitor a patient's treatment progress. Enzyme linked lectin specific assay or ELLSA has been proven to directly detect melanoma derived exosomes from fluid samples. ELLSA directly measures exosome particles in complex solutions, and has already been found capable of detecting exosomes from other sources, including ovarian cancer and tuberculosis-infected macrophages.

    Exosomes, secreted by tumors, are also believed to be responsible for triggering programmed cell death apoptosis of immune cells; interrupting T-cell signaling required to mount an immune response; inhibiting the production of anti-cancer cytokines, and has implications in the spread of metastasis and allowing for angiogenesis.

    It is believed that decreasing the tumor-secreted exosomes in a patient's bloodstream will slow down progression of the cancer while at the same time increasing the patients own immune response. Complementary and alternative medicine CAM treatments are the diverse group of medical and health care systems, practices, and products that are not part of conventional medicine and have not been shown to be effective. Some alternative treatments which have been investigated and shown to be ineffective continue to be marketed and promoted.

    Mindfulness -based interventions appear to facilitate physical and emotional adjustment to life with cancer through symptom reduction, positive psychological growth, and by bringing about favourable changes in biological outcomes. The incidence of concurrent cancer during pregnancy has risen due to the increasing age of pregnant mothers [41] and due to the incidental discovery of maternal tumors during prenatal ultrasound examinations.

    In some cases a therapeutic abortion may be recommended. Radiation therapy is out of the question, and chemotherapy always poses the risk of miscarriage and congenital malformations. Even if a drug has been tested as not crossing the placenta to reach the child, some cancer forms can harm the placenta and make the drug pass over it anyway. Clinical trials are the best way to find new treatments. You might want to explore the different types of cancer clinical trials available to you.

    Use this website to help you search for clinical trials recruiting in Victoria. Recent changes in Commonwealth and state laws mean that medicinal cannabis products can now be used in Australia to assist in the treatment and management of cancer related symptoms and side effects. Medicinal cannabis may be prescribed to people with cancer to stimulate appetite or weight gain, or to manage nausea, vomiting or pain. Understand more about treatments that you may undertake. Find your local treatment centre in metropolitan and regional Victoria.

    Find out more about advanced cancer including what it is, how it is treated, what might happen and what support is available. Understand more about when cancer is diagnosed in children, teen and young adults and how to manage the needs of the child, family, friends and community.

    Understand more about the role genetics has in cancer risk and how to find out more if you are concerned about a family history of cancer. Understand the common reactions people have when they are diagnosed with cancer and suggestions for adjusting to the diagnosis.

    Learn about the importance of exercise and its benefits during and after cancer treatment. Includes tips and example exercise techniques. Understand the grief experienced when losing someone close to you and find out ways to live with the loss.

    Information to assist you with the emotional, physical, practical, spiritual and social challenges you may face now that treatment has finished. Information and tips for people with cancer and their partners to help understand and deal with the ways cancer and its treatment may affect your sexuality.

    Information and support 13 11 20 Support in your language 13 14 50 askanurse cancervic. Our wig service is free, private and personalised. We offer an extensive range of synthetic wigs along with headscarves, beanies and cotton caps. Our Forgotten Cancers Program is committed to improving survival for less common and low survival cancers. Education programs for people who work in a healthcare setting and want to improve their communication skills with patients and families.

    Cancer Council Victoria is a company limited by guarantee governed by a Board of Directors who are advised by committees.

    Options include immunotherapy, hormone therapy and targeted therapy , as well as: Information and support call 13 11 20 13 11 Information in your own language call 13 14 50 13 14 Email a cancer nurse Email. Other languages Website policies and information Contact us Aboriginal communities. Types of cancer Information about the diagnosis and treatment of different cancer types. Treatments Understand more about treatments that you may undertake. Questions for your doctor. Search for a clinical trial.

    Cancer clinical trials - What to know and who to ask - Webinar - Survey. Making decisions about your care. Parking at cancer treatment centres. Advanced cancer Find out more about advanced cancer including what it is, how it is treated, what might happen and what support is available.

    What is advanced cancer? Talking with family and friends. Treatment for advanced cancer. Advance Care Planning Webinars. Children, teens and young adults. Children, teens and young adults Understand more about when cancer is diagnosed in children, teen and young adults and how to manage the needs of the child, family, friends and community. Reactions and emotions to childhood cancer. Life during and after childhood cancer. Talking to kids about cancer.

    Cancer in the school community. Family history of cancer. Victorian Family Cancer Register. Web links - family cancer. Aboriginal communities Cancer information for aboriginal communities. Get checked Early detection offers one of the best chances of cure. Find bowel cancer early. Faecal occult blood tests. Questions about your breasts. Ductal carcinoma in situ. Lobular carcinoma in situ. Limit alcohol Evidence has linked alcohol consumption to various cancers.

    What's a standard drink? Eat a healthy diet. Eat a healthy diet We recommend a healthy body weight, regular exercise and a healthy diet. Be a healthy weight. Be a healthy weight Convincing evidence links obesity to various cancers.

    Be physically active Evidence links physical activity to reduced breast and colon cancer risk. Be SunSmart It's preventable but nearly 2, Australians die of skin cancer each year. Quit smoking Each year 15, Australians are diagnosed with smoking-related cancer. Workplaces Tips to cut your cancer risk in the workplace. Common side effects Cancer and its treatment can result in a range of side effects.

    For instance, the anti-nausea medication used during chemotherapy is a form of supportive therapy. Cancer pain treatment is another form of supportive therapy.

    Palliative care is used in cancer treatment or to treat the symptoms arising from cancer treatment. Palliative care can be provided for months or even years. The most common symptoms treated in palliative care are pain, constipation, nausea, confusion and fatigue. Palliative care is provided in tandem with curative treatment immediately following cancer diagnosis.

    For patients with metastatic cancer, palliative care is of central importance. The procedures used in symptomatic therapy may in part be the same as those used in curative treatment.

    For instance, radiotherapy can reduce metastases, which helps patients feel better. Up to 50 — 90 per cent of cancer patients suffer from treatment fatigue during their illness and periods of treatment. This involves extreme tiredness and fatigue that does not pass simply with sleeping and resting. Further information on treatment fatigue. Research is used to develop cancer treatments. Clinical trials or treatment studies are research studies done with patients.

    Laboratory testing and animal testing precede clinical trials. The advantages and disadvantages of a new form of treatment are studied for a long time before patient trials are started. There are many sorts of clinical trials. They are used, among other things, to:. Many clinical trials study new forms of cancer therapy: With a clinical trial, the personal responsible adhere to a research protocol that carefully specifies what is to be done, when and why.

    Before the start of the trial, the Ethics Committee examines the protocol and independent individuals assess the ethics of the trial. The aims of the research and the practical matters related to being patients in a clinical trial as well as the possible advantages and disadvantages of the new form of treatment are explained to patients before they take part in the trial. If patients do not want to participate in a trial, they will receive treatment as normal according to current treatment recommendations.

    If they wish, patients taking part in trials can stop doing so and transfer to normal treatment. Facts about cancer What is cancer?

    Treatment types

    Cancer treatment is the use of surgery, radiation, medications and other therapies to cure a cancer, shrink a cancer or stop the progression of a. Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy and synthetic lethality. The choice of therapy depends. Learn about the different types of cancer treatment available. Find out which ones work best for you.

    Featured articles



    Comments

    loleg123

    Cancer treatment is the use of surgery, radiation, medications and other therapies to cure a cancer, shrink a cancer or stop the progression of a.

    vumik

    Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy and synthetic lethality. The choice of therapy depends.

    Add Comment