THC and CBD are just two compounds from a family of around bi- and tri- cyclic compounds cannabinoid compounds found naturally in. Marijuana Explore CBD vs. THC and understand the difference between the two natural elements of cannabis. Our expert team breaks it. TheStreet breaks it down for you with all of the marijuana facts. Despite varying public feeling on marijuana, these two separate compounds (CBD vs. The main difference between CBD (cannabidiol) and THC Due to its psychoactive nature, THC has been linked to feelings of Product Features.
THC: Difference Two Of Elements vs. Cannabis Natural Between The The CBD
But another area that can get confusing involves two of the active ingredients in marijuana: Both are natural elements found within the cannabis plant. However, both affect you in different ways.
Every scene you have seen in every movie that involves someone using marijuana is actually a scene of someone experiencing the effects of THC.
Also, things become very funny and you may find yourself very hungry. Research is ongoing on the effects of marijuana on the brain. What is known is that THC interacts with the brain and central nervous system, bonding with receptors in both areas. It acts much in the way of anandamide, a naturally occurring chemical in the body that controls sleeping and eating habits. It also can help treat those who experience depression and combat some of the side effects of cancer patients undergoing chemotherapy.
Some research also has shown that combining THC with CBD has the best affect for different conditions, such as inflammation or pain. In fact, CBD is known to inhibit some of the affects of THC, including short-term memory loss and the anxious feeling some people experience when using certain strains. Users typically take CBD through an oil extract.
Producers now grow hemp specifically for the purpose of creating CBD products. These can be used to treat everything from muscle aches to headaches and even menstrual cramps.
Structurally, however, there is one important difference. It is this seemingly small difference in molecular structure that gives the two compounds entirely different pharmacological properties. As with many of the cannabinoids, THC and CBD have low solubility in water, but good solubility in most organic solvents, particularly lipids and alcohols. Both THC and CBD are present in cannabis in a mixture of acidic forms, which are readily de-carboxylated and chemically altered upon heating, important when you consider that smoking cannabis is the most common form of consumption.
THC is also well known for its ability to bind to glass and plastic. Therefore, THC preparations are typically stored in basic or organic solvents in amber silicate glassware to avoid loss, especially during analytical testing procedures. THC is a potent partial agonist of CB1. It is this stimulation which leads to the major psychotropic effects of cannabis consumption.
CB1 is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system with a particularly high abundance in the brain. As part of the endocannabinoid system it is activated by the endogenous neurotransmitters, anandamide and 2-arachidonoylglycerol, as well as other naturally occurring compounds including the phytocannabinoids found in cannabis.
As a potent partial agonist of CB1, THC stimulates the CB1 receptor leading to the psychotropic effects experienced when consuming cannabis. CBD on the other hand, is classified as a negative allosteric modulator of CB1, meaning it effectively alters the shape of the CB1 receptor.
Through its interactions with the CB1 receptor, CBD is thought to modulate the psychotropic effects of THC by inhibiting its ability to bind to and stimulate the receptor. CBD is able to reduce some of the negative effects of THC by decreasing anxiety, paranoia and the short-term memory impairment often experienced when consuming cannabis. Evidence suggests that a CBD-rich product with little THC can in fact convey therapeutic benefits without having a euphoric or dysphoric effect.
In broad terms, this reflects the consensus of the traditional pharmaceutical industry that a drug with a single active ingredient is easier to develop, test, produce, prescribe and regulate. As evidence for the beneficial effects of combining cannabinoids in medicine increases this may change. Particularly with the growth in popularity of the concept of whole plant medicine.
What is CBD? The 'miracle' cannabis compound that doesn't get you high
Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two primary cannabinoids that occur naturally in the Cannabis sativa plant, most commonly known. We'll take a look at two compounds, CBD vs THC, and compare them on a number of (THC), two natural compounds found in plants of the Cannabis genus. Tetrahydrocannabinoil (THC) and cannabidiol (CBD) are both natural elements found in the cannabis plant. The chemical compositions may.